Remission of Spontaneous Canine Tumors after Systemic Cellular Viroimmunotherapy

Evaluation of matrix metalloproteinases (MMP)-2 and MMP-9 activity in serum and biochemical and hematological parameters in spontaneous canine cutaneous tumors before and after surgical treatment

Recently, matrix metalloproteinases (MMP), in particular the gelatinases MMP-2 and MMP-9, generally considered as tumor markers for clinical applications. A longitudinal 2-years follow-up survey was performed on dogs with cutaneous tumor. Serum samples were obtained from 22 dogs with different cutaneous tumors and 22 health dogs at the time of surgery and one month, three months and one year af...

autoradiography in spontaneous canine tumors: comparison with pimonidazole hypoxia immunohistochemistry

Background: The aim of this study was to compare Cu-diacetyl-bis(N-methylsemicarbazone) (Cu-ATSM) and FDG PET uptake characteristics and Cu-ATSM autoradiography to pimonidazole immunohistochemistry in spontaneous canine sarcomas and carcinomas. Methods: Biopsies were collected from individual tumors between approximately 3 and 25 hours after the intravenous injection of Cu-ATSM and pimonidazole...

Spontaneous remission of hepatocellular carcinoma after massive gastrointestinal haemorrhage.

Remission of disseminated cancer after systemic oncolytic virotherapy.

MV-NIS is an engineered measles virus that is selectively destructive to myeloma plasma cells and can be monitored by noninvasive radioiodine imaging of NIS gene expression. Two measles-seronegative patients with relapsing drug-refractory myeloma and multiple glucose-avid plasmacytomas were treated by intravenous infusion of 10(11) TCID50 (50% tissue culture infectious dose) infectious units of...

Classification and grading of canine malignant mammary tumors

Histological grading is a good parameter to stratify tumors according to their biological aggressiveness. The Elston and Ellis grading method in humans, invasive ductal breast carcinomas and other invasive tumors are routinely used. The aims of this study were classification of mammary gland tumors and also application of a human grading method in canine mammary carcinoma. The samples included ...